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Table 12.21 Effects of Methotrimeprazine on Agitation Post ABI

Author Year

Country

Research Design

PEDro

Sample Size

Methods Outcomes

Maryniak et al. (2001)

Canada

Case Series

N=120

Population: TBI=95, ABI=25; Mean Age=37.8 yr; Gender: Male=89, Female=31.

Intervention: Retrospective review of patients attending an inpatient ABI rehabilitation unit. Patients administered methotrimeprazine (MTZ) were analyzed.

Outcome Measure: Agitated Behaviour Scale.

1.        58% had agitation but 56 patients were treated with MTZ (10-25 mg, 4×/day) with a mean length of treatment of 41.9 day.

2.        MTZ, for the most part (96% of patients), was both safe and effective for controlling agitation.