Select Page

Table 12.26 Effectiveness of Intrathecal Baclofen for Spasticity in Children post ABI

 
Author/ Year/ Country/ Study Design/ N Methods Outcome
Walter et al. (2015) Switzerland Case Series N=3 Population: ABI: Hypoxia=3; Mean Age=4.0 yr; Gender: Male=2, Female=1; Mean Time Post Injury=64.3 days. Treatment: Patients received intrathecal baclofen pump implants and were monitored for a mean of 2315 day (approximately 6.3 yr). Dosage increased from 117 mcg at baseline to 660mcg at the study end. Assessments were conducted at baseline and annually for at least 5 yr. Outcome Measure: Modified Ashworth Scale (MAS), complication rate.
  1. Spasticity on MAS decreased from baseline to post-treatment in the upper and lower extremities.
  2. Five occurrences of pump-related complications were observed including two cases of skin protrusion, one case of infection, one case of lumbar cerebrospinal fluid leak, and one case of intractable spasticity requiring a pump replacement.
PEDro=Physiotherapy Evidence Database rating scale score (Moseley et al., 2002).