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Table 12.38 Effects of Depo-Provera on Sexually Aggressive Behaviour

Author Year   Country   Research Design   PEDro   Sample Size Methods Outcomes

Emory et al. (1995)

USA

Case Series

N=8

 

Population: TBI; Mean Age=17.5 yr; Gender: Male=8, Female=0.

Treatment: Weekly intramuscular injections of Depo-Provera (400 mg) in conjunction with directive, individual-specific counseling for 6mo.

Outcome Measure: Incidence of hypersexual behaviour, change in testosterone level.

1.        Family members report all subjects stopped aberrant behaviour while taking medication.

2.        Blood work revealed a drop in testosterone from 834 to 85 mg/dL; 3 subjects returned to previous patterns after stopping medication (due to inconsistent family support).

3.        3 subjects dramatically improved and did not stop medication.