Mooney & Haas

(1993)

USA

RCT

PEDro=5

N=38

Population: TBI; Mean Age=29.45 yr; Gender: Male=38, Female=0; Mean Time Post Injury=27.08 mo.

Intervention: Patients in the treatment group (n=19) received methylphenidate (30 mg/day). Those in the control group received a placebo (n=19) for 6 wk.

Outcome Measure: State-Trait Anger Scale, the Belligerence cluster score from the Katz Adjustment Scale and the Anger-Hostility factor score of the Profile of Mood States.

1.         Following statistical control over the possible bias (difference in baseline anger scores), there was a significant main effect for the drug treatment (p<0.001).

2.         Analyzing the anger outcome measures, a significant drug by time interaction effect was noted (p=0.002).