| Hernandez et al. 2017
USA
Case Control
N=76
|
Population: TBI; pRBC group (n=40): Median Age=47.5 yr; Gender: Male=23, Female=17; Median GCS=4. Plasma group (n=36): Median Age=65 yr; Gender: Male=24, Female=12; Median GCS=8.
Intervention: All patients with multiple injuries who received remote damage control blood transfusions at a Level 1 trauma center between 2002 and 2013 were retrospectively identified. Outcomes of patients who received thawed plasma transfusions were compared with those who received pRBCs alone.
Outcome Measure: Glasgow Outcome Score Extended (GOSE), Disability Rating Scale (DRS). |
- Patients who received plasma (Median GOSE=7) demonstrated significantly higher neurological function at discharge compared with the pRBC only group (Median GOSE=5.5)(p<0.001). This improvement persisted at follow-up (p<0.001).
2. At discharge, DRS scores were also significantly higher in the plasma group (Median DRS=2) compared to the pRBC only group (Median DRS=9)(p<0.001). This improvement persisted at follow-up (p<0.001). |
