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Table 4.1 Constraint Induced Movement Therapy for Upper Extremity Rehabilitation Post ABI

Author, Year Country Study Design Sample Size Methods Outcome
Shaw et al. (2005) USA Pre-Post N=22   Population: TBI; Mean Age=39.3yr; Gender: Male=14, Female=8; Mean Time Post Injury=8.9yr. Intervention: Participants received constraint induced movement therapy (CIMT; 6hr, 5 d/wk for 2wk) in the laboratory engaging in massed practice shaping or task specific procedures while wearing a protective safety mitt on their less-affected upper limb (UL) for ≥90% of the time. Participants were encouraged to use the mitt outside the lab as well. Outcome Measure: Fugl Meyer (FM) Motor Performance Assessment, Wolf Motor Function Test (WMFT), and Motor Activity Log (MAL). 1.        Significant improvements in real-world use across all post-intervention testing occasions as measured by the MAL (mean change=1.6, p<0.001). 2.        Significant post-treatment improvements in more affected ULFM scores (mean change=4.2, p<0.001), and WMFT scores (mean change=0.4, p<0.01). 3.        Based on the FM scores, the largest gains were in the upper arm, compared to the hand or wrist. 4.        Based on a median split (57%) of adherence to mitt wearing outside the lab, less-adherent participants had smaller treatment gains than those who were more-adherent. 5.        On the MAL, less adherent participants showed a trend towards smaller gains than more adherent subjects (p=0.065).
Page & Levine (2003) USA Pre-Post N=3   Population: TBI; Mean Age=21yr; Gender: Male=2, Female=1. Intervention: Physical and occupational therapy sessions (30min each, 3x/wk for 10 wk) were provided. The less affected upper limb was also restrained (5hr/day for 5days/wk) using modified constraint induced therapy (mCIT). Outcome Measure: Action Research Arm Test (ARAT), Motor Activity Log (MAL), and Wolf Motor Function Test (WMFT). 1.        Pre-intervention subjects exhibited learned non-use (MAL, Amount of Use scores <1.0). 2.        After the intervention, MAL scores improved: Amount of use=2.0 and quality of use=2.2. Subjects 1, 2 and 3 had functional improvements on the ARAT (14.0, 5.5, and 6.0 respectively) and the WMFT (1.15, 1.7 and 1.35 respectively).