Table 6.5 The Effect of Transcranial Direct Current Stimulation on Attention Post ABI
Author Year Country Research Design PEDro Sample Size |
Methods |
Outcome |
South Korea RCT PEDro=7 N=13 |
Population: Experimental Group (N=7): Mean age=42.42yr; Gender: Male=5, Female=2; Mean time post-injury=3.85 months; Mean GCS=13.71. Control Group (N=6): Mean age=41.33yr; Gender: Male=4, Female=2; Mean time post-injury=3.88 months; Mean GCS=13.66. Intervention: Individuals received either rTMS or sham rTMS for 30mins 5 times a week, for 2 weeks. Outcomes: Montgomery-Asberg Depression Rating Scale (MADRS), Trail Making Test (TMT), Stroop Color Word Test (SCWT). |
1. The experimental group experienced significant within group differences on the MADRS (p<0.05), TMT (p<0.05), and SCWT (p<0.05). 2. No significant within group differences were seen for the control group. 3. Following intervention, the experimental group had significantly lower scores on the MADRS (p<0.05), TMT (p<0.05), and SCWT (p<0.05). *Lower scores indicate improved performance on TMT and SCWT. |
Sacco et al. (2016) Italy RCT PEDro=4 N=32 |
Population: TBI. Mean Time Post Injury=8.73yr; Severity: Severe=32, Moderate=0, Mild=0. Treatment Group (TG, n=16): Mean Age=37.7; Gender: Male=12, Female=4. Control Group (CG, n=16): Mean Age=35.2; Gender: Male=14, Female=2. Intervention: Participants were randomized to receive transcranial direct current stimulation (tDCS, TG) or sham tDCS (CG) with computer-assisted training (2/d, 5d). Outcomes were assessed at baseline (T0), before treatment (T1), after treatment (T2), and 1-month follow-up (T3). Outcome Measures: Test for the Examination of Attention, Divided Attention subtest (DA); Repeatable Battery for the Assessment of Neurological Status (RBANS). |
1. For DA, the TG performed significantly better at T2 compared to T0 and T1, with faster reaction times (p=0.004) and fewer omission errors (p<0.0001).
2. For DA, the CG did not perform better at T2 compared to T0 and T1. 3. For DA, there was a significant interaction between time (T0/T1 vs T2) and group (TG vs CG), for both reaction time (p=0.05) and omission errors (p=0.03). 4. On RBANS, the TG showed a non-significant improvement in performance on attention task (p=0.057), but no improvement on visual-spatial abilities, semantic fluency, working memory, and long-term memory. |