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Table 8.17 Effects of Valproic Acid on Agitation and Aggression Post TBI

Author

Year

Country

Research Design

PEDro

Sample Size

Methods Outcomes

Wroblewski et al.

(1997)

USA

Case Series

N=5

Population: TBI; Mean Age=38.2yr; Gender: Male=4, Female=1.

Intervention: Patients received valproic acid for destructive and aggressive behaviours.

Outcome Measure: Aberrant Behaviour Checklist.

1.         All patient showed a substantial reduction in target behaviours.