Table 8.21 Effects of Methotrimeprazine on Agitation and Aggression Post ABI
Author Year Country Research Design PEDro Sample Size |
Methods | Outcomes |
(2001) Canada Case Series N=120 |
Population: TBI=95, ABI=25; Mean Age=37.8yr; Gender: Male=89, Female=31. Intervention: Retrospective review of patients attending an inpatient ABI rehabilitation unit, and some received methotrimeprazine (MTZ). Outcome Measure: Agitated Behaviour Scale. |
1. Fifty-eight percent had agitation but 56 patients were treated with MTZ (10-25 mg, 4x/day) with a mean length of treatment of 41.9 days. 2. MTZ, was both safe and effective for controlling agitation in 96% of patients. |