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Table 8.22 Effects of Droperidol on Agitation and Aggression Post ABI

Author

Year

Country

Research Design

PEDro

Sample Size

Methods Outcome

Stanislav & Childs

(2000)

USA

Case Series

N=27

Population: TBI; Gender: Male=21, Female=6.

Intervention: Patients received intramuscular injection of droperidol as needed to relieve agitation.

Outcome Measure: Episodes of agitation.

1.         Mean dose was 3.25 mg; a single dose reduced agitation in 96% of patients.

2.         Time to achieve calming following episodes of agitation was significantly shortened with droperidol compared to haloperidol, lorazepam, or diphenhydramine (p=0.02).