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Table 9.14 Neuroendocrine Interventions Summary (Mitchell & Owens, 1996)

 
Condition Treatment Dosage & Delivery
Hypogonadism Testosterone therapy (males) Estrogen therapy (females) Oral therapy Subcutaneous implant Intramuscular injection Transdermal patches and gels Short term treatment due to risks
ACTH Deficiency Hydrocortisone Prednisolone 20mg in morning and 10mg in early evening given orally, intramuscularly, or IV 5-7.5mg/d given orally (1×/d)
TSH Deficiency Synthetic TSH (Levothyroxine) 1mg given orally before breakfast
GHD Synthetic GH (Somatropin) or GHRH 0.06mg/kg given subcutaneously or intramuscularly (3×/wk)
SIADH ADH inhibitor (Conivaptan) 20mg/d given by intravenous for short periods of time
DI Desmopressin 0.1-0.4mL/d intranasally