Noe et al. (2007)

USA

Case Series

N=5

Population: TBI; Mean Age=26.8 yr; Gender: Male=3, Female=2; Mean GCS Score=6; Mean Time Post Injury=54.6 days.

Treatment: Ziprasidone (30-80mg/d for 35-68d) was given to participants.

Outcome Measure: Agitation Behaviour Scale (ABS).

1.       Mean dose of the drug was 52.8 mg/days.

2.       Scores on the ABS decreased within the first 14 days (27.3 to 18).

3.       Scores on the disinhibition portion of the ABS decreased from 28.6 to 17.1, while scores on the aggressiveness subsection of the scale decreased from 26.1 to 20.4.

4.       No side effects were noted.