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Table 12.47 The Effect of Pramiracetam on Memory Post ABI

Author Year   Country   Research Design   PEDro   Sample Size   Methods   Outcomes

McLean Jr. et al. (1991)

USA

RCT

PEDro=5

N=4

 

Population: TBI; Age Range=23-37 yr; Gender: Male=4, Female=0.

Intervention: Patients were treated in two, 3 wk blocks of oral pramiracetam (400 mg, 2x/d) and placebo over 12wk.

Outcome Measure:  Wechsler Memory Scale (WMS), Selective Reminding Test, Trail Making Test A&B, Finger Tapping Test, Digit Symbol Test, Word Fluency Test.

1.        Improvements in immediate and delayed recall in the WMS (logical memory and selecting reminding test) were found for the treatment group.

*statistical values not provided in the study