Table 7.3 Light Therapy for the Management of Fatigue Post ABI
Author Year Country Study Design Sample Size |
Methods | Outcome |
(2020) France RCT PEDro=7 NInitial=20, NFinal=20 |
Population: TBI=20; Intervention Group (Blue-enriched white light therapy, BWL; n=10): Mean Age=34.20±10.73yr; Sex Ratio=2.33; Mean Time Post Injury=7.93±9.99yr; Severity: Mean GCS=5.88±1.55. Control Group (No light therapy, N-BWL; n=10): Mean Age=39±9.81yr; Sex Ratio=1.22; Mean Time Post Injury=10.02±10.71yr; Severity: Mean GCS=6±1.83. Intervention: Participants were randomly allocated to receive light therapy (blue-enriched white light, 30min upon waking for 4wk) or no light therapy. Outcome measures were assessed at baseline, 2wk, 4wk and 6wk. Outcome Measures: Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS), Hamilton Depression Scale (HDS-17), Short Form Health Survey (SF-12). | 1. BWL significantly improved fatigue severity (FSS, p=.026) from baseline to 4wk. (p<.001); however, improvements disappeared at 6wk, 2wk following treatment cessation. 2. BWL significantly improved measures of depression from baseline to 4wk (HADS17, p=.04). Improvements were maintained at 6wk. 3. No significant differences in quality of life (SF-12, p>.05), sleep quality (PSQI, p>.05), or daytime sleepiness (ESS, p>.05) were observed between groups. |
(2014) Australia RCT PEDro=6 N=30 |
Population: TBI=30; Mean Age= 42yr; Male=24, Female=6; Mean Time Post Injury=1106d; Severity: Mild=7, Moderate=8, Severe=15. Intervention: Participants were randomized to one of three home-based treatment groups: blue light therapy (n=10), yellow light therapy (n=10) or the no treatment control group (n=10). Participants were instructed to use the device for 45min each morning, within 2hr of waking up, for 4wk. Assessments were conducted at baseline, 4wk and 8wk. Outcome Measure: Fatigue Severity Scale (FSS), Epworth Sleepiness Scale (ESS), Pittsburgh Sleep Quality Index (PSQI). |
1. Compared to the control group, the blue light therapy group showed a significantly greater reduction in fatigue (FSS; p<0.001) and a significant reduction in daytime sleepiness (ESS; p<0.01). However, no significant improvements were observed in the yellow light therapy group when compared to controls. 2. There was no significant change in PSQI score in any treatment condition (p>0.05). |