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Table 4.12 Percutaneous Phenol Block for the Treatment of Spasticity Post ABI

Author Year Country Study Design Sample Size Methods Outcome
Keenan et al. (1990) USA Case Series N=17 Population: TBI; Mean Age=25yr; Gender: Male=12, Female=5; Mean Time Post Injury=6mo. Intervention: Subjects received a phenol block (3ml of 5% phenol solution in sterile saline) followed by a daily program of active/passive range of motion therapy. Assessments conducted pre-post block, 24hr after, then at weekly intervals while patients were hospitalized for rehabilitation.  Post discharge follow-up occurred for a minimum of 2yr. Outcome Measure: Muscle tone/control, Range of Motion. 1.        Ninety-three percent of extremities showed a short-term decrease in motor tone and improved resting position of the elbow. 2.        Maximum improvements occurred 4wk post block. 3.        Resting position improved from 120° to 69°, active arc increased from 46° to 60°, and passive arc from 65° to 118°. 4.        At follow-up (mean 27mo post injection), 9 extremities that had relief of spasticity, had recurrence of flexor tone and loss of motion in the elbow.
Garland et al. (1984) USA Case Series N=11   Population: TBI=11; Mean Age=24yr; Gender: Male=8, Female=3; Mean Time Post Injury=5.8mo. Intervention: Subjects received percutaneous phenol injections (1-2ml of 3 or 5% phenol solution) at motor points of spastic wrist and finger flexors identified using a nerve stimulator. Injected muscles included: the flexor carpi radialis, flexor carpi ulnaris, flexor digitorum sublimus, flexor digitorum profundus, and flexor pollicis longus. Outcome Measure: Resting Angle of Wrist, Passive/active Extension of Wrist. 1.        Mean resting position of the wrist prior to injection was 53°. Nine patients increased resting extension by a mean of 34° and 2 patients lost a mean of 15° of extension. 2.        Overall, there was a mean increase in resting wrist angle following motor point injections of 25°. 3.        Active wrist extension improved an average of 30°. Mean increase in passive wrist extension with finger flexed of 5°.