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Table 8.23 Effects of Haloperidol on Agitation and Aggression Post ABI

Author

Year

Country

Research Design

PEDro

Sample Size

Methods  Outcomes

Rao et al.

(1985)

USA

Case Series

N=26

 

Population: TBI; Age Range=16-48yr; Injury Severity: Severe.

Intervention: Retrospective review of patients attending an inpatient ABI rehabilitation unit whose agitation was treated with haloperidol (n=11; 2-15 mg/day) and those who were not (n=15).

Outcome Measure: Patient Evaluation Conference Systems.

1.         Those treated had a longer length of post-traumatic amnesia (p<0.03).

2.         No statistically significant differences were shown between those who were and were not treated in terms of independent living at discharge (64% versus 60%) or independence in managing behaviour (40% versus 60%).

3.         Three untreated patients obtained independence in intellectual skills but none of the treated patients achieved it.